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Aarhus Universitet

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Østjylland
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Indrykket 08-04-2021

Laboratory Technician or Technical Administrative Person within the laboratory for Angiogenesis and Vascular Heterogeneity

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position within the laboratory for Angiogenesis and Vascular Heterogeneity as per 1 June 2021 or as soon as possible thereafter. The position is a permanent full-time position.

We offer a vibrant international research environment where English is the preferred language in the laboratory, at meetings and at seminars. The Department employs some 450 people and covers a range of research areas within Biomedicine. We contribute to the Bachelor’s degree programs in medicine, molecular medicine, odontology and the Master’s degree programs in biomedical engineering and medical chemistry. Our infrastructure is well developed with modern laboratories, core and animal facilities. You will work either in the brand new ‘Skou Building’ or similar as we are in the process of modernizing our old facilities. You can read more about the department here and about the faculty here.

The group
The lab of Peter Carmeliet, the laboratory for Angiogenesis and Vascular Heterogeneity, recently started at the Department of Biomedicine at Aarhus University and is closely linked to his lab at the Flanders institute for biotechnology (VIB, Leuven, Belgium). There will be regular interaction, which offers opportunities for short term training periods in Leuven. Both the newly starting Aarhus and the Leuven lab, apply their expertise and therapeutic focus to evaluate and deliver novel therapeutic concepts into clinical development with the ambition to change the life of patients with vasculature-related disorders. Standard gene modulation strategies (conditional gene targeting/silencing/overexpression) are exploited as well as sophisticated novel disruptive high-throughput multi-omics approaches (bulk and scRNAseq, scG&T, scATAC; metabolomics, etc.) and computational modelling, both for hypothesis generating and hypothesis testing experiments. For instance, recent successful efforts in generating a single cell transcriptome atlas of ECs from various healthy and pathological (including tumor) tissues from preclinical models and clinical samples have revealed the existence of previously unknown endothelial cell subtypes, including endothelial cells with a resident endothelial stem cell signature, and endothelial cells with a putative immunosurveillance role, key findings being taken into further investigation. In addition, endothelial cell-specific Genome scale metabolic models (GEM) were generated and successfully used to predict metabolic enzymes/pathways essential for endothelial cell growth.

Your job responsibilities
As laboratory technician or technical administrative person, your primary tasks are focused on research and logistic support. You will contribute to the laboratory for Angiogenesis and Vascular Heterogeneity by: participating in research projects focussing on angiogenesis and vascular heterogeneity; through logistics and stock management of products, consumables and devices. You will support the team in discovering and validating novel target candidates. In your daily work, you will work under the supervision and in close collaboration with postdoctoral scientists and have a close interaction with other colleagues.

Your main tasks will consist of:

  • Performing cell culture techniques: isolation and culture of endothelial cells and other cell types.
  • Executing western blotting, PCR, quantitative PCR, glycolysis and fatty oxidation assay.
  • Histology: fixation, embedding, cutting (vibratome or cryostat) and (immuno)staining of human and murine tissue.
  • Imaging and analysis of tissue slides.
  • Viral transduction experiments.
  • Ordering of product, consumables and devices. Deliveries follow-up. Stock management.
Being familiar with the ordering system of Aarhus University is an advantage.
  • Mouse colony management. Performing animal experiments and assisting in animal experiments.
  • Communicating and reporting laboratory results in a professional manner and in digital format (e.g. excel)
  • Keep laboratory and equipment clean and organized to ensure safety in the laboratory.

You will report to Prof. P. Carmeliet.

Your competences
Selected candidates should be reliable and well organized. The work requires independence and demands flexibility and accuracy. Furthermore, the candidate should have good interpersonal skills and be interested in working within an international team (partially located in Leuven, Belgium).

The ideal candidate should fulfil the following qualifications:
  • A background within laboratory technologies, biotechnology, biomedicine, biology or biochemistry.
  • Solid experience as a laboratory technician in a research lab
  • Proven experience in molecular biology, cell culture or biochemistry work and techniques
  • Candidates are familiar with Microsoft Word and Excel.
  • Experience in histology, imaging and animal surgery will be considered as an advantage.
  • Experience with the ordering system of the Aarhus University is a plus
  • Good English and Danish communication skills, both oral and written, are expected
  • You are a team player with a results and problem-solving oriented spirit
  • You are proactive, motivated and enthusiastic

Questions about the position
If you have any questions about the position, please contact Professor Peter Carmeliet: peter.carmeliet@kuleuven.beor Katie Van Geyte katie.vangeyte@biomed.au.dk

Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10, DK-8000 Aarhus C, Denmark.

We expect to conduct interviews in week 17 or 18.

Terms of employment
Terms of employment and pay are regulated in accordance with the applicable collective agreement.

Application
Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Indication of education (a copy of the diplomas should be uploaded)
  • References/recommendations can be uploaded separately in the recruitment system

We refer to the faculty’s Guideline for applicants.

All interested candidates are encouraged to apply, regardless of their personal background.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.

Aarhus University
Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,000 employees, and has an annual revenues of EUR 885 million. Learn more at www.international.au.dk/

Deadline: 26 April 2021

 


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Virksomhedsinformation
Aarhus Universitet
Høegh-Guldbergs Gade 10
8000 Aarhus C
Kontaktperson
 
Tlf:
87150000
Adresse:
8000 Aarhus C
Danmark
Praktisk information
Oprettet:
08-04-2021
Udløber:
26-04-2021
Kviknummer:
LJA-81933481
Jobtype:
Fuldtid
Arbejdsområde:
Procesteknik og fødevarer
Beliggenhed
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